Kanada\u2019n\u0131n British Columbia \u00dcniversitesinde (UBC) g\u00f6rev yapan bir grup bilim insan\u0131n\u0131n, A, B, ve AB grubu kanlar\u0131, O Rh (-) kan grubuna d\u00f6n\u00fc\u015ft\u00fcren ve al\u0131c\u0131n\u0131n kan tipine bak\u0131lmaks\u0131z\u0131n hastalarla uyumlu hale getirebilecek bir teknik geli\u015ftirdikleri bildirildi.<\/p>\n
\u00c7al\u0131\u015fmay\u0131 ger\u00e7ekle\u015ftiren bilim heyetinden Biyokimya Uzman\u0131 Stephen Withers, Kanada bas\u0131n\u0131na yapt\u0131\u011f\u0131 a\u00e7\u0131klamada, farkl\u0131 kan t\u00fcrlerini genel verici kabul edilen O Rh (-) kan grubuna d\u00f6n\u00fc\u015ft\u00fcrmenin bir yolunu bulduklar\u0131n\u0131 a\u00e7\u0131klad\u0131.<\/p>\n
Withers, insanlardaki d\u00f6rt kan tipini birbirinden ay\u0131ran \u015feyin, k\u0131rm\u0131z\u0131 kan h\u00fccrelerinin y\u00fczeyindeki minik \u015feker molek\u00fclleri oldu\u011funu, A, B ve AB grubu kanlarda, ba\u011f\u0131\u015f\u0131kl\u0131k sistemi taraf\u0131ndan tan\u0131nan farkl\u0131 \u015feker molek\u00fclleri olmas\u0131na kar\u015f\u0131n O Rh (-) kan grubunun bu \u015feker molek\u00fcllerine sahip olmad\u0131klar\u0131n\u0131 ve bu y\u00fczden O Rh (-) kan grubunun t\u00fcm al\u0131c\u0131larla uyumlu oldu\u011funu hat\u0131rlatt\u0131.<\/p>\n
Withers, A, B ve AB grubu kanlar\u0131 O Rh (-) kan grubu gibi di\u011fer kanlarla uyumlu hale getirmenin \u00e7\u00f6z\u00fcm\u00fcn\u00fcn, \u015feker molek\u00fcllerini etkin bir \u015fekilde kesebilen molek\u00fcler makas\u0131 bulmak oldu\u011funu belirtti.<\/p>\n
Ara\u015ft\u0131rmac\u0131lar\u0131n 1980’lerin ba\u015f\u0131ndan bu yana bu makas \u00fczerinde \u00e7al\u0131\u015ft\u0131\u011f\u0131n\u0131, belli bir noktaya kadar ba\u015far\u0131 sa\u011fland\u0131\u011f\u0131n\u0131 ifade eden Withers, arad\u0131klar\u0131 kayna\u011f\u0131, insan ba\u011f\u0131rsa\u011f\u0131ndaki bakterilerde bulduklar\u0131n\u0131 s\u00f6yledi.<\/p>\n
Withers, ba\u011f\u0131rsak duvarlar\u0131n\u0131n, farkl\u0131 k\u0131rm\u0131z\u0131 kan h\u00fccrelerinde bulunan ayn\u0131 \u015feker molek\u00fcllerine sahip olan m\u00fcsin ad\u0131 verilen \u015feker yap\u0131lar\u0131yla kapl\u0131 oldu\u011funu belirterek, “Bu y\u00fczden insan ba\u011f\u0131rsa\u011f\u0131 mikrobiyomu, arad\u0131\u011f\u0131m\u0131z\u0131 bulmak i\u00e7in iyi bir yer gibi g\u00f6r\u00fcn\u00fcyordu.” dedi.<\/p>\n
Withers, bu ama\u00e7la insan d\u0131\u015fk\u0131s\u0131ndan ald\u0131klar\u0131 ba\u011f\u0131rsak bakterilerinden 20 bin farkl\u0131 DNA \u00f6rne\u011fi \u00e7\u0131kard\u0131klar\u0131n\u0131 ve onlardan \u015fekerleri par\u00e7alamakta iyi olan yeni bir enzim s\u0131n\u0131f\u0131n\u0131 ke\u015ffettiklerini kaydetti.<\/p>\n
Bunun, daha \u00f6nceki ara\u015ft\u0131rmalarda elde edilenden 30 kat daha h\u0131zl\u0131 ayr\u0131labilen bir enzim oldu\u011funu s\u00f6yleyen Withers, bu y\u00fcksek verimlilik seviyesinin, kan d\u00f6n\u00fc\u015f\u00fcm s\u00fcrecinde daha az enzime ihtiya\u00e7 duymas\u0131 anlam\u0131na gelece\u011fini, bunun da daha d\u00fc\u015f\u00fck \u00fcretim maliyetleri ve fakat daha da \u00f6nemlisi transf\u00fczyon sonras\u0131 daha az enzimin filtrelenmesi demek oldu\u011funa dikkati \u00e7ekti.<\/p>\n
Withers, yeni kan d\u00f6n\u00fc\u015ft\u00fcrme tekni\u011finin hayata ge\u00e7mesinin biraz zaman alabilece\u011fini ve d\u00f6n\u00fc\u015ft\u00fcr\u00fclm\u00fc\u015f kanlar\u0131n, transf\u00fczyonlarda kullan\u0131lmak \u00fczere onaylanmadan \u00f6nce kapsaml\u0131 g\u00fcvenlik testlerinin uygulanmas\u0131n\u0131n gerekebilece\u011fini s\u00f6zlerine ekledi.<\/p>\n","protected":false},"excerpt":{"rendered":"
British Columbia \u00dcniversitesindeki bilim insanlar\u0131, A, B, ve AB grubu kanlar\u0131, O Rh (-) kan grubuna d\u00f6n\u00fc\u015ft\u00fcren bir teknik geli\u015ftirdi.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"jnews-multi-image_gallery":[],"jnews_single_post":[],"jnews_primary_category":[],"footnotes":""},"categories":[22,19],"tags":[],"coauthors":[],"class_list":["post-73337","post","type-post","status-publish","format-standard","hentry","category-bilim","category-dunya"],"_links":{"self":[{"href":"https:\/\/www.nordicturk.com\/arsiv\/20122025\/wp-json\/wp\/v2\/posts\/73337","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.nordicturk.com\/arsiv\/20122025\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.nordicturk.com\/arsiv\/20122025\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.nordicturk.com\/arsiv\/20122025\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.nordicturk.com\/arsiv\/20122025\/wp-json\/wp\/v2\/comments?post=73337"}],"version-history":[{"count":0,"href":"https:\/\/www.nordicturk.com\/arsiv\/20122025\/wp-json\/wp\/v2\/posts\/73337\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.nordicturk.com\/arsiv\/20122025\/wp-json\/wp\/v2\/media?parent=73337"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.nordicturk.com\/arsiv\/20122025\/wp-json\/wp\/v2\/categories?post=73337"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.nordicturk.com\/arsiv\/20122025\/wp-json\/wp\/v2\/tags?post=73337"},{"taxonomy":"author","embeddable":true,"href":"https:\/\/www.nordicturk.com\/arsiv\/20122025\/wp-json\/wp\/v2\/coauthors?post=73337"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}