{"id":9441,"date":"2017-05-11T12:50:05","date_gmt":"2017-05-11T10:50:05","guid":{"rendered":"https:\/\/haberler.dk\/tr\/?p=9441"},"modified":"2021-10-03T06:33:35","modified_gmt":"2021-10-03T04:33:35","slug":"kolon-kanseri-tedavisinde-umut-veren-gelisme","status":"publish","type":"post","link":"https:\/\/www.nordicturk.com\/arsiv\/20122025\/kolon-kanseri-tedavisinde-umut-veren-gelisme\/9441\/","title":{"rendered":"Kolon kanseri tedavisinde umut veren geli\u015fme"},"content":{"rendered":"

Uluda\u011f \u00dcniversitesi’nde 2011’den bu yana yap\u0131lan \u00e7al\u0131\u015fmada, “barbipalladium” ad\u0131 verilen bile\u015fi\u011fin kolon kanseri tedavisinde kullan\u0131labilece\u011fi konusunda bulgulara ula\u015f\u0131ld\u0131.<\/p>\n

<\/p>\n

\u00dcniversitenin Kimya B\u00f6l\u00fcm\u00fc \u00d6\u011fretim \u00dcyesi Prof. Dr. Veysel Turan, T\u0131p Fak\u00fcltesi Biyokimya Ana Bilim Dal\u0131 \u00d6\u011fretim \u00dcyesi Prof. Dr. Engin Ulukaya ve Yrd. Do\u00e7. Dr. Ceyda \u0130\u00e7sel’in bursiyer olarak g\u00f6rev ald\u0131\u011f\u0131 T\u00dcB\u0130TAK destekli \u00e7al\u0131\u015fmada, olu\u015fturulan yeni bile\u015fi\u011fin kolon kanserine kar\u015f\u0131 y\u00fcksek antikanser etki g\u00f6sterebilece\u011fine y\u00f6nelik bulgular elde edildi.<\/p>\n

Kanserli t\u00fcm\u00f6rlerin b\u00fcy\u00fcmesini durdurmakla kalmay\u0131p zaman i\u00e7inde t\u00fcm\u00f6rlerin boyutlar\u0131n\u0131 \u015fu an piyasadaki ila\u00e7lara g\u00f6re \u00e7ok daha etkili bir bi\u00e7imde k\u00fc\u00e7\u00fcltt\u00fc\u011f\u00fc tespit edilen bile\u015fik i\u00e7in patent al\u0131nd\u0131.<\/p>\n

\u0130nsanlar \u00fczerinde yap\u0131lacak deneylerin ard\u0131ndan birtak\u0131m a\u015famalardan ge\u00e7ecek bile\u015fi\u011fin yakla\u015f\u0131k 4 y\u0131l sonra ila\u00e7 a\u015famas\u0131na gelebilece\u011fi tahmin ediliyor.<\/p>\n

“T\u00fcm\u00f6rleri \u00f6nemli derecede k\u00fc\u00e7\u00fcltt\u00fc”<\/strong><\/p>\n

Turan, U\u00dc’de ger\u00e7ekle\u015ftirilen bas\u0131n toplant\u0131s\u0131nda, multidisipliner olarak, anorganik kimya ve biyoanorganik kimya alan\u0131nda y\u00fcr\u00fct\u00fclen \u00e7al\u0131\u015fmalar\u0131n semeresini verdi\u011fini s\u00f6yledi.<\/p>\n

Yap\u0131lan \u00e7al\u0131\u015fma sonucunda laboratuvarda tasarlanan ve sentezlenen maddelerden birinin \u00f6nemli derecede antikanser etki g\u00f6sterdi\u011fini tespit ettiklerini belirten Turan, \u015f\u00f6yle konu\u015ftu:<\/p>\n

“\u00d6zellikle kolon kanseri \u00fczerinde etkisi g\u00f6zlenen bu bile\u015fik, piyasada tedavi ama\u00e7l\u0131 kullan\u0131lan platin grubu antikanser ila\u00e7lar\u0131n muadili olabilecek hatta onlardan daha etkili oldu\u011funu g\u00f6rd\u00fc\u011f\u00fcm\u00fcz bir ila\u00e7. Bunu kendi laboratuvar\u0131m\u0131zda sentezledik. Biyolojik aktivite \u00e7al\u0131\u015fmalar\u0131n\u0131 Engin hocan\u0131n laboratuvar\u0131nda y\u00fcr\u00fctt\u00fck. Bu y\u00fcksek etkiyi g\u00f6rd\u00fckten sonra fare deneylerini yapmam\u0131z gerekiyordu. Bu deneyler de \u00e7al\u0131\u015fma ortaklar\u0131m\u0131zdan Selanik \u00dcniversitesinde y\u00fcr\u00fct\u00fcld\u00fc ve farelerde yeti\u015ftirilen t\u00fcm\u00f6rleri \u00f6nemli derecede k\u00fc\u00e7\u00fcltt\u00fc\u011f\u00fc ve mevcut piyasada kullan\u0131lan ila\u00e7lardan \u00e7ok daha etkili oldu\u011fu sonucuna ula\u015ft\u0131k.”<\/p>\n

Daha sonra \u00e7al\u0131\u015fmaya incelemeli uluslararas\u0131 patent ald\u0131klar\u0131n\u0131 anlatan Turan, tasarlad\u0131klar\u0131 bile\u015fi\u011fe bulu\u015f sahipleri olarak “barbipalladium” ad\u0131n\u0131 verdiklerini bildirdi.<\/p>\n

Turan, birtak\u0131m deneyler daha yapacaklar\u0131n\u0131 dile getirerek, “\u00d6nce laboratuvar deneylerini kanserli h\u00fccreler \u00fczerinde, ondan sonra fareler, daha sonra da insan deneyleri \u00fczerinde olacak.” diye konu\u015ftu.<\/p>\n

Cumhurba\u015fkan\u0131 Recep Tayyip Erdo\u011fan’\u0131n da deste\u011fini beklediklerini vurgulayan Turan, “Cumhurba\u015fkan\u0131m\u0131z desteklerini verirse bu inand\u0131\u011f\u0131m\u0131z bir bilgi ve sonu\u00e7. Bunun ila\u00e7 olma olas\u0131l\u0131\u011f\u0131 \u00e7ok y\u00fcksek.” dedi.<\/p>\n

Turan, bile\u015fik \u00fczerinde kar\u015f\u0131la\u015fmal\u0131 testler de yapt\u0131klar\u0131n\u0131 anlatarak, \u015f\u00f6yle devam etti:<\/p>\n

“Kanserli h\u00fccreler \u00fczerinde di\u011fer ila\u00e7lardan \u00e7ok daha etkili. T\u00fcm\u00f6rlerin b\u00fcy\u00fcmesini durdurmas\u0131 ve k\u00fc\u00e7\u00fcltmesi bak\u0131m\u0131ndan da \u00e7ok daha etkili. Bu ilac\u0131n \u00f6zelli\u011fi, y\u00fcksek dozlarda verildi\u011finde fareler canl\u0131 fakat t\u00fcm\u00f6r yok oluyor. \u0130nsanlarda da piyasadaki ila\u00e7lara g\u00f6re zehirleme a\u00e7\u0131s\u0131ndan daha az etkili fakat t\u00fcm\u00f6rleri k\u00fc\u00e7\u00fcltmesi a\u00e7\u0131s\u0131ndan daha y\u00fcksek etkili olaca\u011f\u0131n\u0131 d\u00fc\u015f\u00fcn\u00fcyoruz.”<\/p>\n

“Giri\u015fimciler sahip \u00e7\u0131kmal\u0131”<\/strong><\/p>\n

\u0130stinye \u00dcniversitesi T\u0131p Fak\u00fcltesi Biyokimya Ana Bilim Dal\u0131 \u00d6\u011fretim \u00dcyesi Prof. Dr. Engin Ulukaya da bile\u015fi\u011fin “insan \u00e7al\u0131\u015fmas\u0131” a\u015famas\u0131n\u0131n arefesinde olduklar\u0131n\u0131, bug\u00fcne kadar “faz 1” olarak adland\u0131r\u0131lan bu onkolojik \u00e7al\u0131\u015fman\u0131n T\u00fcrkiye’de hi\u00e7 yap\u0131lmad\u0131\u011f\u0131n\u0131 aktard\u0131.<\/p>\n

Yunanistan ile temasa ge\u00e7ti\u011fini, faz 1 insan \u00e7al\u0131\u015fmas\u0131n\u0131 yapacak merkez arand\u0131\u011f\u0131n\u0131 s\u00f6yleyen Ulukaya, “E\u011fer fon bulabilirsek bu bile\u015fik insanlarda denenecek a\u015famaya geldi ve denenecektir. Bundan ba\u015far\u0131l\u0131 olarak \u00e7\u0131karsa faz 2 ve faz 3 daha sonra da eczane raflar\u0131nda bu \u00fclkenin bir kanser ilac\u0131n\u0131 g\u00f6rmeye \u00e7ok arzu ediyoruz.” ifadelerini kulland\u0131.<\/p>\n

“\u00c7ok stratejik bir \u00fcr\u00fcn”<\/strong><\/p>\n

Ulukaya, “Kanser ila\u00e7lar\u0131n\u0131n \u00fclkeye y\u0131ll\u0131k getirisi 8-10 milyar dolar aras\u0131nda de\u011fi\u015fiyor. Dolay\u0131s\u0131yla \u00e7ok stratejik bir \u00fcr\u00fcn.” dedi.<\/p>\n

U\u00dc Rekt\u00f6r\u00fc Prof. Dr. Yusuf Ulcay, \u00e7al\u0131\u015fmada eme\u011fi ge\u00e7enleri tebrik ederek, “Ger\u00e7ekle\u015fti\u011fi taktirde T\u00fcrkiye’de yap\u0131lm\u0131\u015f ilk kanser ilac\u0131 olacak. Bu a\u00e7\u0131dan \u00e7ok \u00f6nemli. Patenti almak \u00f6nemli ama bu patent ilaca d\u00f6n\u00fc\u015fmedi\u011fi m\u00fcddet\u00e7e bunun anlam\u0131 yok. T\u00fcrkiye’deki ila\u00e7 firmalar\u0131n\u0131n bunu sahiplenmesini arzu ediyoruz. T\u00fcrkiye’deki giri\u015fimcilerin bu i\u015fe sahip \u00e7\u0131kmas\u0131 laz\u0131m.” de\u011ferlendirmesinde bulundu.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Uluda\u011f \u00dcniversitesi’nde 2011’den bu yana yap\u0131lan \u00e7al\u0131\u015fmada, “barbipalladium” ad\u0131 verilen bile\u015fi\u011fin kolon kanseri tedavisinde kullan\u0131labilece\u011fi konusunda bulgulara ula\u015f\u0131ld\u0131.<\/p>\n","protected":false},"author":3,"featured_media":9443,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"jnews-multi-image_gallery":[],"jnews_single_post":[],"jnews_primary_category":[],"footnotes":""},"categories":[6],"tags":[],"coauthors":[],"class_list":["post-9441","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik"],"yoast_head":"\nKolon kanseri tedavisinde umut veren geli\u015fme<\/title>\n<meta name=\"description\" content=\"Uluda\u011f \u00dcniversitesi'nde 2011'den bu yana yap\u0131lan \u00e7al\u0131\u015fmada, "barbipalladium" ad\u0131 verilen bile\u015fi\u011fin kolon kanseri tedavisinde kullan\u0131labilece\u011fi konusunda bulgulara ula\u015f\u0131ld\u0131.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.nordicturk.com\/arsiv\/20122025\/kolon-kanseri-tedavisinde-umut-veren-gelisme\/9441\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Kolon kanseri tedavisinde umut veren geli\u015fme\" \/>\n<meta property=\"og:description\" content=\"Uluda\u011f \u00dcniversitesi'nde 2011'den bu yana yap\u0131lan \u00e7al\u0131\u015fmada, "barbipalladium" ad\u0131 verilen bile\u015fi\u011fin kolon kanseri tedavisinde kullan\u0131labilece\u011fi konusunda bulgulara ula\u015f\u0131ld\u0131.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.nordicturk.com\/arsiv\/20122025\/kolon-kanseri-tedavisinde-umut-veren-gelisme\/9441\/\" \/>\n<meta property=\"og:site_name\" content=\"NordicTurk\" \/>\n<meta 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